Xiangru Lu Selected Research

Retinal Dehydrogenase

1/2020	Sapropterin reduces coronary artery malformation in offspring of pregestational diabetes mice.
4/2015	Pregestational diabetes induces fetal coronary artery malformation via reactive oxygen species signaling.

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Xiangru Lu Research Topics

Disease

12	Myocardial Infarction 01/2016 - 07/2008
8	Endotoxemia 01/2016 - 10/2003
7	Heart Failure 01/2017 - 06/2002
6	Infarction (Infarctions) 01/2018 - 11/2010
6	Sepsis (Septicemia) 01/2016 - 02/2005
4	Congenital Heart Defects (Congenital Heart Defect) 01/2022 - 02/2014
4	Myocardial Ischemia (Ischemic Heart Diseases) 01/2016 - 01/2009
4	Ischemia 09/2011 - 07/2004
3	Hypoxia (Hypoxemia) 01/2020 - 04/2009
2	Atrioventricular Septal Defect 11/2018 - 02/2014
2	Cardiomegaly (Heart Hypertrophy) 01/2017 - 10/2004
2	Cardiac Arrhythmias (Arrythmia) 01/2016 - 10/2009
2	Reperfusion Injury 10/2013 - 09/2011
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2019
1	Double Outlet Right Ventricle 11/2018
1	Diabetes Mellitus 11/2018
1	Hypertrophy 01/2017
1	Hypothermia 01/2016
1	Cicatrix (Scar) 05/2011
1	Heart Rupture 05/2011
1	Rupture 05/2011
1	Wounds and Injuries (Trauma) 11/2010
1	Anemia 01/2010
1	Ventricular Fibrillation 10/2009
1	Necrosis 03/2009
1	Abdominal Aortic Aneurysm 05/2005
1	Atherosclerosis 05/2005

Drug/Important Bio-Agent (IBA)

9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016 - 10/2003
4	LipopolysaccharidesIBA 01/2016 - 04/2005
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2012
3	CytokinesIBA 01/2016 - 03/2012
3	Stem Cell FactorIBA 09/2014 - 09/2009
3	Hemoglobins (Hemoglobin)IBA 03/2012 - 01/2010
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 09/2011 - 08/2002
2	Retinal DehydrogenaseIBA 01/2020 - 04/2015
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2020 - 04/2015
2	Streptozocin (Streptozotocin)FDA Link 01/2019 - 11/2018
2	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2018 - 03/2012
2	CalciumIBA 01/2016 - 03/2012
2	Tetracycline (Achromycin)FDA LinkGeneric 09/2014 - 10/2013
2	Trans-Activators (Trans-Acting Factor)IBA 09/2014 - 10/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2014 - 12/2002
2	Mitogen-Activated Protein KinasesIBA 01/2014 - 03/2012
2	Messenger RNA (mRNA)IBA 03/2012 - 10/2004
2	Erythropoietin FDA Link 11/2010 - 01/2009
2	salicylhydroxamic acid (SHAM)IBA 07/2008 - 10/2004
2	NADH oxidaseIBA 04/2005 - 02/2005
1	Nicotine FDA Link 01/2022
1	CateninsIBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 11/2018
1	sapropterin (tetrahydrobiopterin)FDA Link 11/2018
1	acetovanillone (apocynin)IBA 01/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	GTP-Binding Proteins (G-Protein)IBA 01/2017
1	Amino Acids FDA Link 01/2017
1	ChloridesIBA 01/2016
1	NSC 23766IBA 01/2016
1	IceIBA 01/2016
1	Isoflurane FDA LinkGeneric 01/2016
1	Superoxides (Superoxide)IBA 01/2016
1	Cadherins (E-Cadherin)IBA 04/2015
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2015
1	Acetylcysteine (Siran)FDA LinkGeneric 02/2014
1	Drinking WaterIBA 02/2014
1	AnnexinsIBA 01/2014
1	Annexin A5IBA 01/2014
1	Adenosine Triphosphatases (ATPase)IBA 03/2012
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 09/2011
1	ErbB Receptors (EGF Receptor)IBA 05/2011
1	Cetuximab (Erbitux)FDA Link 05/2011
1	CollagenIBA 05/2011
1	Epidermal Growth Factor (EGF)IBA 05/2011
1	Hydroxyproline (4 Hydroxyproline)IBA 05/2011
1	Phosphotransferases (Kinase)IBA 05/2011
1	Transforming Growth Factors (Transforming Growth Factor)IBA 05/2011
1	Tissue Inhibitor of Metalloproteinase-3IBA 05/2011
1	Matrix Metalloproteinases (MMPs)IBA 05/2011
1	IronIBA 01/2010
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 10/2009
1	Verapamil (Calan)FDA LinkGeneric 10/2009
1	Chemokine CXCL12IBA 04/2009
1	Chemotactic FactorsIBA 04/2009
1	Conditioned Culture MediaIBA 04/2009
1	Heme Oxygenase-1IBA 01/2009
1	EnzymesIBA 02/2006
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 02/2006
1	Biotin (Vitamin H)FDA Link 02/2006
1	Caspase 3 (Caspase-3)IBA 02/2006
1	ImmunosorbentsIBA 02/2006
1	fasudil (AT 877)IBA 05/2005
1	ApolipoproteinsIBA 05/2005
1	Angiotensin IIIBA 05/2005

Therapy/Procedure

4	Ligation 01/2016 - 10/2004
3	Blood Transfusion (Blood Transfusions) 03/2012 - 01/2010
1	Sutures (Suture) 01/2016
1	Therapeutics 01/2016
1	Injections 03/2010
1	Tourniquets 02/2006
1	Vascular Surgical Procedures 02/2006